Prior to the introduction of Viagra in the late 1990s, there were very few medical treatments for sexual dysfunction. A few other drugs, such as Cialis, have come onto the market in the following years. While these drugs have helped treat sexual dysfunction in millions of men, millions more men and women still struggle with the condition because they cannot use Viagra or Cialis. Or it doesn’t work for them. Fortunately, treatment with peptides can help improve symptoms of sexual dysfunction.
Sexual dysfunction is common in the United States – for both men and for women. About 30 million American men between the ages of 40 to 70 suffer from erectile dysfunction. Another 30 million American women experience sexual dysfunction, such as low desire, lack of orgasm, or not finding sex pleasurable.
Doctors typically prescribe medications known as PDE5 inhibitors, such as the brand names Viagra and Cialis, to treat erectile dysfunction in men. PDE5 inhibitors are vasodilators, which mean they expand blood vessels in the penis to cause an erection. These drugs do not increase desire, though, which means they may not be completely effective in treating sexual dysfunction in men and they are not suitable for women.
Worse still, PDE5 inhibitors may “contraindicated” in some cases, which means these drugs may not be right for all patients. Specifically, PDE5 is contraindicated in patients who take nitrate medications for chest pain associated with heart disease.
Peptide Treatment for Sexual Dysfunction
Treatment with peptides may be the right choice for men and women experiencing sexual dysfunction.
Peptides are natural compounds that serve many functions throughout the body. Without getting too technical, peptides are similar to proteins, except a bit smaller. In fact, you can put a bunch of peptides together to make proteins.
There are several different types of peptides. Certain hormones are perhaps the most well known type of peptide. Many medical professionals refer to hormones as the body’s chemical messengers because of the way hormones influence various functions of the body. Cortisol is the “fight or flight” hormone that tells the body to get ready for battle, for example. Testosterone and estrogen are sex hormones that control the reproductive system and cause other effects.
Hormones work by attaching to special cell receptors around the body, somewhat like a boat “docking” into a slip. Cortisol docks to cortisol receptors in body cells, while testosterone attaches to androgen receptors. The action of the hormone attaching to the receptor causes the cell to behave differently.
Most hormones are produced by endocrine glands. The adrenaline glands that sit on top of the kidneys produce cortisol, for instance, while the testicles produce testosterone. One special type of hormone, known as a neurohormone, is produced by nerve cells. Neurohormones affect the central nervous system, which includes the brain and spinal cord. When a neurohormone attaches to a receptor, it activates nerve cells, known as neurons.
Therapeutic Peptide PT-141
Doctors prescribe peptides, such as neurohormones, to cause different therapeutic effects and treat various problems around the body. One peptide in particular, PT-141, works with the central nervous system and the sexual center of the brain. Specifically, PT-141 activates neurons in the hypothalamus. The hypothalamus reacts by telling the pituitary gland to release sex hormones associated with sexual arousal.
In other words, the peptide PT-141 treats sexual dysfunction by stimulating the sexual center of the brain to cause desire, instead of merely opening up blood vessels to cause an erection. This makes PT-141 a great alternative to Viagra or Cialis for men whose sexual dysfunction goes beyond erectile dysfunction or for men who cannot take vasodilators. PT-141 is also an option for women with sexual dysfunction.
PT-141, also known as bremelanotide, is easy to use. Patients use it only when needed, unlike Cialis Daily and other medications that need to be taken every day. This potent peptide works well for most people. In fact, PT-141 works in 80 percent of men who do not respond to Viagra.
Unlike Viagra and Cialis, there are no contraindications for the use of PT-141 – patients taking nitrate medications for heart problems can still take PT-141 for sexual dysfunction. The peptide PT-141 is also less expensive dose-for-dose than Viagra.
For more information about PT-141 for the treatment of sexual dysfunction, speak to your Age Management physician.
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